Endothelial replicative senescence delayed by the inhibition of MTORC1 signaling involves MicroRNA-107. [electronic resource]
Producer: 20190328Description: 64-73 p. digitalISSN:- 1878-5875
- A549 Cells
- Adaptor Proteins, Signal Transducing -- genetics
- Cell Cycle Proteins
- Cell Proliferation -- drug effects
- Cellular Senescence -- drug effects
- Cyclin-Dependent Kinase Inhibitor p16 -- genetics
- G1 Phase Cell Cycle Checkpoints -- drug effects
- Gene Expression Regulation
- Human Umbilical Vein Endothelial Cells
- Humans
- Mechanistic Target of Rapamycin Complex 1 -- antagonists & inhibitors
- MicroRNAs -- genetics
- PTEN Phosphohydrolase -- genetics
- Phosphoproteins -- genetics
- RNA, Messenger -- genetics
- RNA, Small Interfering -- genetics
- Regulatory-Associated Protein of mTOR -- antagonists & inhibitors
- Ribosomal Protein S6 -- genetics
- Signal Transduction
- Sirolimus -- pharmacology
- TOR Serine-Threonine Kinases -- antagonists & inhibitors
- beta-Galactosidase -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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