AR Signaling in Prostate Cancer Regulates a Feed-Forward Mechanism of Androgen Synthesis by Way of HSD3B1 Upregulation. [electronic resource]
Producer: 20190226Description: 2884-2890 p. digitalISSN:- 1945-7170
- Androgens -- metabolism
- Androstenedione -- metabolism
- Animals
- Antineoplastic Agents, Hormonal -- pharmacology
- Benzamides
- Cell Line, Tumor
- Dehydroepiandrosterone -- metabolism
- Gene Expression Regulation, Neoplastic -- drug effects
- Humans
- Male
- Metribolone -- pharmacology
- Mice
- Multienzyme Complexes -- drug effects
- Neoplasm Transplantation
- Nitriles
- Orchiectomy
- Phenylthiohydantoin -- analogs & derivatives
- Progesterone Reductase -- drug effects
- Prostatic Neoplasms -- genetics
- Prostatic Neoplasms, Castration-Resistant -- genetics
- Receptors, Androgen -- drug effects
- Steroid Isomerases -- drug effects
- Testosterone
- Testosterone Congeners -- pharmacology
- Up-Regulation
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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