Synthesis, antitumour activities and molecular docking of thiocarboxylic acid ester-based NSAID scaffolds: COX-2 inhibition and mechanistic studies. [electronic resource]
Producer: 20180619Description: 989-998 p. digitalISSN:- 1475-6374
- Anti-Inflammatory Agents, Non-Steroidal -- chemical synthesis
- Antineoplastic Agents
- Carboxylic Acids -- chemistry
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Cyclooxygenase 2 -- metabolism
- Cyclooxygenase 2 Inhibitors -- chemical synthesis
- Dose-Response Relationship, Drug
- Drug Screening Assays, Antitumor
- Humans
- Molecular Docking Simulation
- Molecular Structure
- Structure-Activity Relationship
- Sulfhydryl Compounds -- chemistry
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Publication Type: Journal Article
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