Activating PIK3CD mutations impair human cytotoxic lymphocyte differentiation and function and EBV immunity. [electronic resource]
Producer: 20191112Description: 276-291.e6 p. digitalISSN:- 1097-6825
- Adolescent
- Adult
- Aged
- B-Lymphocytes -- immunology
- CD8-Positive T-Lymphocytes -- immunology
- Cell Differentiation -- genetics
- Cellular Senescence -- genetics
- Child
- Child, Preschool
- Class I Phosphatidylinositol 3-Kinases -- genetics
- Epstein-Barr Virus Infections -- genetics
- Gain of Function Mutation
- Genetic Diseases, Inborn -- genetics
- Herpesvirus 4, Human -- immunology
- Humans
- Immunologic Surveillance -- genetics
- Killer Cells, Natural -- immunology
- Male
- Middle Aged
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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