Reduction of vascular leakage by imatinib is associated with preserved microcirculatory perfusion and reduced renal injury markers in a rat model of cardiopulmonary bypass. [electronic resource]
Producer: 20190107Description: 1165-1175 p. digitalISSN:- 1471-6771
- Acute Kidney Injury -- etiology
- Animals
- Capillary Permeability -- drug effects
- Cardiopulmonary Bypass -- adverse effects
- Cytokines -- biosynthesis
- Disease Models, Animal
- Drug Evaluation, Preclinical -- methods
- Endothelium, Vascular -- drug effects
- Imatinib Mesylate -- pharmacology
- Inflammation Mediators -- metabolism
- Male
- Microcirculation -- drug effects
- Microscopy, Electron
- Oxygen Consumption -- drug effects
- Premedication -- methods
- Protein Kinase Inhibitors -- pharmacology
- Random Allocation
- Rats, Wistar
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Publication Type: Journal Article
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