Human carbonic anhydrase-8 AAV8 gene therapy inhibits nerve growth factor signaling producing prolonged analgesia and anti-hyperalgesia in mice. [electronic resource]
Producer: 20181105Description: 297-311 p. digitalISSN:- 1476-5462
- Analgesia -- methods
- Animals
- Biomarkers, Tumor -- biosynthesis
- Dependovirus -- genetics
- Disease Models, Animal
- Genetic Therapy -- methods
- Humans
- Hyperalgesia -- genetics
- Inositol 1,4,5-Trisphosphate Receptors -- drug effects
- Male
- Mice
- Mice, Inbred C57BL
- Nerve Growth Factor -- antagonists & inhibitors
- Neuralgia -- genetics
- Neurons -- metabolism
- Pain Management -- methods
- Phosphorylation
- Signal Transduction
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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