Targeting of EGFR, VEGFR2, and Akt by Engineered Dual Drug Encapsulated Mesoporous Silica-Gold Nanoclusters Sensitizes Tamoxifen-Resistant Breast Cancer. [electronic resource]
Producer: 20190624Description: 2698-2713 p. digitalISSN:- 1543-8392
- Animals
- Antineoplastic Agents -- pharmacology
- Apoptosis -- drug effects
- Breast Neoplasms -- drug therapy
- Catechin -- analogs & derivatives
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Chemical Engineering
- Drug Carriers -- chemistry
- Drug Resistance, Neoplasm -- drug effects
- ErbB Receptors -- metabolism
- Female
- Gold -- chemistry
- Humans
- Metal Nanoparticles -- chemistry
- Mice, Nude
- Piperidines -- pharmacology
- Porosity
- Proto-Oncogene Proteins c-akt -- metabolism
- Quinazolines -- pharmacology
- Silicon Dioxide -- chemistry
- Tamoxifen -- pharmacology
- Treatment Outcome
- Vascular Endothelial Growth Factor Receptor-2 -- metabolism
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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