Preparative electrochemical reduction of 2-amino-6-chloropurine and synthesis of 6-deoxyacyclovir, a fluorescent substrate of xanthine oxidase and a prodrug of acyclovir. [electronic resource]
Producer: 19880503Description: 701-7 p. digitalISSN:- 0302-4369
- 2-Aminopurine -- analogs & derivatives
- Acyclovir -- analogs & derivatives
- Adenine -- analogs & derivatives
- Animals
- Antiviral Agents -- chemical synthesis
- Electrolysis
- Guinea Pigs
- Herpes Simplex -- drug therapy
- Hydrogen-Ion Concentration
- Magnetic Resonance Spectroscopy
- Oxidation-Reduction
- Polarography
- Prodrugs -- chemical synthesis
- Simplexvirus -- drug effects
- Spectrometry, Fluorescence
- Spectrophotometry, Ultraviolet
- Viral Plaque Assay
- Xanthine Oxidase -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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