Benzoxazinone-containing 3,5-dimethylisoxazole derivatives as BET bromodomain inhibitors for treatment of castration-resistant prostate cancer. [electronic resource]
Producer: 20180619Description: 542-559 p. digitalISSN:- 1768-3254
- Animals
- Antineoplastic Agents -- chemical synthesis
- Benzoxazines -- chemistry
- Cell Movement -- drug effects
- Cell Proliferation -- drug effects
- Cell Survival -- drug effects
- Dose-Response Relationship, Drug
- Drug Screening Assays, Antitumor
- Humans
- Isoxazoles -- chemistry
- Male
- Molecular Structure
- Prostatic Neoplasms, Castration-Resistant -- drug therapy
- Proteins -- antagonists & inhibitors
- Rats
- Rats, Sprague-Dawley
- Structure-Activity Relationship
- Tumor Cells, Cultured
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Publication Type: Journal Article
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