QbD-based development of α-linolenic acid potentiated nanoemulsion for targeted delivery of doxorubicin in DMBA-induced mammary gland carcinoma: in vitro and in vivo evaluation. [electronic resource]
Producer: 20181217Description: 1313-1334 p. digitalISSN:- 2190-3948
- Animals
- Anthracenes -- adverse effects
- Breast Neoplasms
- Cell Proliferation -- drug effects
- Cell Survival -- drug effects
- Doxorubicin -- administration & dosage
- Drug Synergism
- Emulsions
- Female
- Humans
- MCF-7 Cells
- Mammary Neoplasms, Experimental -- chemically induced
- Mitochondrial Membranes -- drug effects
- Models, Molecular
- Nanoparticles -- chemistry
- Piperidines -- adverse effects
- Rats
- Reactive Oxygen Species -- metabolism
- Xenograft Model Antitumor Assays
- alpha-Linolenic Acid -- administration & dosage
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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