Sphinganine effects on chemoattractant-induced diacylglycerol generation, calcium fluxes, superoxide production, and on cell viability in the human neutrophil. Delivery of sphinganine with bovine serum albumin minimizes cytotoxicity without affecting inhibition of the respiratory burst. [electronic resource]
Producer: 19880414Description: 3818-22 p. digitalISSN:- 0021-9258
- Calcium -- blood
- Cell Survival -- drug effects
- Cytosol -- metabolism
- Diglycerides -- blood
- Glycerides -- blood
- Humans
- In Vitro Techniques
- Kinetics
- N-Formylmethionine Leucyl-Phenylalanine -- pharmacology
- Neutrophils -- cytology
- Oxygen Consumption
- Serum Albumin, Bovine -- pharmacology
- Sphingosine -- analogs & derivatives
- Superoxides -- blood
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Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
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