Mechanistic Distinctions between CHK1 and WEE1 Inhibition Guide the Scheduling of Triple Therapy with Gemcitabine. [electronic resource]
Producer: 20190613Description: 3054-3066 p. digitalISSN:- 1538-7445
- Animals
- Antineoplastic Combined Chemotherapy Protocols -- pharmacology
- Cell Cycle Proteins -- antagonists & inhibitors
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Checkpoint Kinase 1 -- antagonists & inhibitors
- DNA Damage -- drug effects
- DNA Replication -- drug effects
- Deoxycytidine -- analogs & derivatives
- Drug Synergism
- Female
- Humans
- Mice
- Mice, Inbred BALB C
- Mice, Nude
- Nuclear Proteins -- antagonists & inhibitors
- Protein-Tyrosine Kinases -- antagonists & inhibitors
- Xenograft Model Antitumor Assays -- methods
- Gemcitabine
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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