Glucocorticoids Inhibit Oncogenic RUNX1-ETO in Acute Myeloid Leukemia with Chromosome Translocation t(8;21). [electronic resource]
Producer: 20190408Description: 2189-2201 p. digitalISSN:- 1838-7640
- Animals
- Antineoplastic Agents -- pharmacology
- Apoptosis -- drug effects
- Cell Differentiation -- drug effects
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Chromosomes, Human, Pair 11 -- genetics
- Chromosomes, Human, Pair 8 -- genetics
- DNA -- metabolism
- Dexamethasone -- pharmacology
- Gene Expression Regulation, Leukemic -- drug effects
- Glucocorticoids -- pharmacology
- Humans
- Leukemia, Myeloid, Acute -- genetics
- Mice, Inbred NOD
- Mice, SCID
- Neoplastic Stem Cells -- drug effects
- Oncogene Proteins, Fusion -- antagonists & inhibitors
- RNA, Long Noncoding
- Receptors, Glucocorticoid -- metabolism
- Transcriptome -- genetics
- Translocation, Genetic
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
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