Down-regulation of TRAF4 targeting RSK4 inhibits proliferation, invasion and metastasis in breast cancer xenografts. [electronic resource]
Producer: 20180914Description: 810-816 p. digitalISSN:- 1090-2104
- Animals
- Breast Neoplasms -- genetics
- Cell Line, Tumor
- Cell Proliferation
- Down-Regulation
- Female
- Gene Expression Regulation, Neoplastic
- Gene Knockdown Techniques
- Humans
- Lentivirus -- metabolism
- Mice, Inbred BALB C
- Mice, Nude
- NF-kappa B -- metabolism
- Neoplasm Invasiveness
- Neoplasm Metastasis
- Proto-Oncogene Proteins c-akt -- metabolism
- RNA Interference
- RNA, Small Interfering -- metabolism
- Ribosomal Protein S6 Kinases, 90-kDa -- metabolism
- Signal Transduction
- TNF Receptor-Associated Factor 4 -- genetics
- Transfection
- Up-Regulation -- genetics
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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