Unexpected cancer-predisposition gene variants in Cowden syndrome and Bannayan-Riley-Ruvalcaba syndrome patients without underlying germline PTEN mutations. [electronic resource]
Producer: 20180619Description: e1007352 p. digitalISSN:- 1553-7404
- Adolescent
- Adult
- Aged
- Child
- Child, Preschool
- DNA Glycosylases -- genetics
- DNA Mutational Analysis
- Female
- Genes, BRCA1
- Genes, BRCA2
- Genetic Predisposition to Disease
- Genetic Variation
- Germ-Line Mutation
- Hamartoma Syndrome, Multiple -- genetics
- Humans
- Infant
- Male
- Middle Aged
- Neoplasms, Multiple Primary -- genetics
- Oncogenes
- PTEN Phosphohydrolase -- genetics
- Prospective Studies
- Proto-Oncogene Proteins c-ret -- genetics
- Proto-Oncogene Proteins p21(ras) -- genetics
- Tuberous Sclerosis Complex 2 Protein
- Tumor Suppressor Proteins -- genetics
- Exome Sequencing
- Xeroderma Pigmentosum Group D Protein -- genetics
- Young Adult
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Publication Type: Journal Article; Multicenter Study; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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