NXY-059, a Failed Stroke Neuroprotectant, Offers No Protection to Stem Cell-Derived Human Neurons. [electronic resource]
Producer: 20181022Description: 2158-2165 p. digitalISSN:- 1532-8511
- Benzenesulfonates -- pharmacology
- Cell Death -- drug effects
- Cell Hypoxia -- drug effects
- Cell Survival -- drug effects
- Cells, Cultured
- Coculture Techniques
- Dose-Response Relationship, Drug
- Drug Evaluation, Preclinical
- Embryonic Stem Cells -- drug effects
- Fibroblasts -- physiology
- Glucose -- deficiency
- Humans
- Hydrogen Peroxide -- toxicity
- L-Lactate Dehydrogenase -- metabolism
- Neurons -- drug effects
- Neuroprotective Agents -- pharmacology
- Nitroprusside -- toxicity
- Oxidative Stress -- drug effects
- Single-Blind Method
- Treatment Failure
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Publication Type: Journal Article; Randomized Controlled Trial
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