Evaluation of novel TGR5 agonist in combination with Sitagliptin for possible treatment of type 2 diabetes. [electronic resource]
Producer: 20181227Description: 1849-1852 p. digitalISSN:- 1464-3405
- Animals
- Binding Sites
- Diabetes Mellitus, Type 2 -- drug therapy
- Drug Therapy, Combination
- Female
- Glucagon-Like Peptide 1 -- metabolism
- Half-Life
- Humans
- Hypoglycemic Agents -- chemistry
- Imidazoles -- chemistry
- Mice
- Mice, Inbred C57BL
- Molecular Docking Simulation
- Protein Structure, Tertiary
- Receptors, G-Protein-Coupled -- agonists
- Sitagliptin Phosphate -- therapeutic use
- Structure-Activity Relationship
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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