Targeting Sphingosine Kinase Isoforms Effectively Reduces Growth and Survival of Neoplastic Mast Cells With D816V-KIT. [electronic resource]
Producer: 20190625Description: 631 p. digitalISSN:- 1664-3224
- Adamantane -- analogs & derivatives
- Animals
- Apoptosis
- Carcinogenesis
- Cell Proliferation
- Cell Survival
- DNA Repair
- Hematologic Neoplasms -- genetics
- Humans
- Hydrazines -- pharmacology
- Mast Cells -- physiology
- Mastocytosis -- genetics
- Mice
- Mice, Knockout
- Mutation -- genetics
- Phosphotransferases (Alcohol Group Acceptor) -- antagonists & inhibitors
- Protein Isoforms -- antagonists & inhibitors
- Proto-Oncogene Proteins c-kit -- genetics
- Pyrazoles -- pharmacology
- Pyridines -- pharmacology
- Tumor Cells, Cultured
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
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