MLL5 suppresses antiviral innate immune response by facilitating STUB1-mediated RIG-I degradation. [electronic resource]
Producer: 20181226Description: 1243 p. digitalISSN:- 2041-1723
- Animals
- CRISPR-Cas Systems
- Cytoplasm -- metabolism
- DEAD Box Protein 58 -- metabolism
- DNA Damage
- DNA-Binding Proteins -- metabolism
- Female
- HEK293 Cells
- Histone-Lysine N-Methyltransferase -- metabolism
- Humans
- Immunity, Innate
- Male
- Mice
- Mice, Inbred C57BL
- Proteasome Endopeptidase Complex -- metabolism
- RNA Interference
- Rhabdoviridae Infections -- immunology
- Signal Transduction
- Ubiquitin-Protein Ligases -- metabolism
- Ubiquitination
- Vesicular stomatitis Indiana virus
- Virus Replication
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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