The uremic toxin hippurate promotes endothelial dysfunction via the activation of Drp1-mediated mitochondrial fission. [electronic resource]
Producer: 20181012Description: 303-313 p. digitalISSN:- 2213-2317
- Animals
- Aorta -- cytology
- Atherosclerosis -- genetics
- Dynamins
- Endothelial Cells -- drug effects
- GTP Phosphohydrolases -- genetics
- Gene Expression Regulation -- drug effects
- Hippurates -- metabolism
- Humans
- Inflammation -- metabolism
- Intercellular Adhesion Molecule-1 -- genetics
- Microtubule-Associated Proteins -- genetics
- Mitochondrial Dynamics -- drug effects
- Mitochondrial Proteins -- genetics
- Nitric Oxide Synthase Type III -- genetics
- Oxidative Stress -- drug effects
- Rats
- Reactive Oxygen Species -- metabolism
- Renal Insufficiency, Chronic -- genetics
- von Willebrand Factor -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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