Screening Regulatory Element Function with CRISPR/Cas9-based Epigenome Editing. [electronic resource]
Producer: 20190204Description: 447-480 p. digitalISSN:- 1940-6029
- CRISPR-Cas Systems
- Cloning, Molecular -- methods
- Clustered Regularly Interspaced Short Palindromic Repeats
- Epigenesis, Genetic
- Gene Editing -- methods
- Gene Expression Profiling -- methods
- Gene Knock-In Techniques -- methods
- Gene Library
- HEK293 Cells
- High-Throughput Screening Assays -- methods
- Humans
- K562 Cells
- Luminescent Proteins -- genetics
- RNA, Guide, CRISPR-Cas Systems -- genetics
- Regulatory Sequences, Nucleic Acid
- Red Fluorescent Protein
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
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