mROS-TXNIP axis activates NLRP3 inflammasome to mediate renal injury during ischemic AKI. [electronic resource]
Producer: 20190308Description: 43-53 p. digitalISSN:- 1878-5875
- Acute Kidney Injury -- immunology
- Animals
- Antioxidants -- metabolism
- Carrier Proteins -- metabolism
- Cell Proliferation
- Cells, Cultured
- Inflammasomes -- immunology
- Inflammation -- immunology
- Interleukin-1beta -- metabolism
- Male
- Mice
- Mice, Inbred C57BL
- Mice, Knockout
- Mitochondria -- immunology
- NLR Family, Pyrin Domain-Containing 3 Protein -- physiology
- Organophosphorus Compounds -- metabolism
- Piperidines -- metabolism
- Reactive Oxygen Species -- metabolism
- Reperfusion Injury -- immunology
- Thioredoxins -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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