Pharmacological Inhibition of Necroptosis Protects from Dopaminergic Neuronal Cell Death in Parkinson's Disease Models. [electronic resource]
Producer: 20190527Description: 2066-2079 p. digitalISSN:- 2211-1247
- 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine
- Animals
- Apoptosis -- drug effects
- Cell Differentiation -- drug effects
- Disease Models, Animal
- Dopaminergic Neurons -- drug effects
- GTP Phosphohydrolases -- genetics
- Induced Pluripotent Stem Cells -- drug effects
- Lysosomes -- drug effects
- Male
- Membrane Potential, Mitochondrial -- drug effects
- Mice, Inbred C57BL
- Mitochondria -- drug effects
- Mutation -- genetics
- Necrosis
- Neural Stem Cells -- drug effects
- Neuroprotective Agents -- pharmacology
- Oxidative Stress -- drug effects
- Parkinson Disease -- pathology
- Small Molecule Libraries -- pharmacology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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