De novo fatty acid synthesis by Schwann cells is essential for peripheral nervous system myelination. [electronic resource]
Producer: 20190318Description: 1353-1368 p. digitalISSN:- 1540-8140
- Animals
- Cells, Cultured
- Fatty Acid Synthase, Type I -- genetics
- Fatty Acids -- biosynthesis
- Female
- Lipogenesis -- drug effects
- Male
- Mice, 129 Strain
- Mice, Inbred C57BL
- Mice, Inbred DBA
- Mice, Knockout
- Myelin Sheath -- metabolism
- Nerve Fibers, Myelinated -- drug effects
- PPAR gamma -- agonists
- Rosiglitazone -- pharmacology
- Schwann Cells -- drug effects
- Sciatic Nerve -- cytology
- Signal Transduction
- Transcription, Genetic
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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