The MAZ transcription factor is a downstream target of the oncoprotein Cyr61/CCN1 and promotes pancreatic cancer cell invasion via CRAF-ERK signaling. [electronic resource]
Producer: 20190114Description: 4334-4349 p. digitalISSN:- 1083-351X
- Adenocarcinoma -- genetics
- Animals
- Apoptosis
- Biomarkers, Tumor -- genetics
- Carcinoma, Pancreatic Ductal -- genetics
- Cell Movement
- Cell Proliferation
- Cysteine-Rich Protein 61 -- genetics
- DNA-Binding Proteins -- genetics
- Epithelial-Mesenchymal Transition
- Female
- Gene Expression Regulation, Neoplastic
- Humans
- Male
- Mice
- Mice, Inbred C57BL
- Mice, Nude
- Mitogen-Activated Protein Kinase 1 -- genetics
- Mitogen-Activated Protein Kinase 3 -- genetics
- Neoplasm Invasiveness
- Neoplastic Stem Cells -- metabolism
- Pancreatic Neoplasms -- genetics
- Prognosis
- Signal Transduction
- TNF Receptor-Associated Factor 3 -- genetics
- Transcription Factors -- genetics
- Tumor Cells, Cultured
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
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