N-acetyl cysteine protects anti-melanoma cytotoxic T cells from exhaustion induced by rapid expansion via the downmodulation of Foxo1 in an Akt-dependent manner. [electronic resource]
Producer: 20190228Description: 691-702 p. digitalISSN:- 1432-0851
- Acetylcysteine -- pharmacology
- Animals
- Cells, Cultured
- Forkhead Box Protein O1 -- metabolism
- Free Radical Scavengers -- pharmacology
- Gene Expression Regulation, Neoplastic -- drug effects
- Humans
- Immunotherapy, Adoptive
- Lymphocyte Activation
- Melanoma -- drug therapy
- Mice
- Phosphatidylinositol 3-Kinases -- metabolism
- Proto-Oncogene Proteins c-akt -- metabolism
- Signal Transduction
- T-Lymphocytes, Cytotoxic -- immunology
No physical items for this record
Publication Type: Journal Article
There are no comments on this title.
Log in to your account to post a comment.