Discovery of Potent Benzocycloalkane Derived Diapophytoene Desaturase Inhibitors with an Enhanced Safety Profile for the Treatment of MRSA, VISA, and LRSA Infections. [electronic resource]
Producer: 20190620Description: 208-217 p. digitalISSN:- 2373-8227
- Animals
- Anti-Bacterial Agents -- chemical synthesis
- Cell Line
- Cell Survival -- drug effects
- Cycloparaffins -- chemical synthesis
- Disease Models, Animal
- Drug-Related Side Effects and Adverse Reactions -- epidemiology
- Enzyme Inhibitors -- chemical synthesis
- Epithelial Cells -- drug effects
- Humans
- Inhibitory Concentration 50
- Methicillin Resistance
- Mice
- Pigments, Biological -- analysis
- Staphylococcal Infections -- drug therapy
- Staphylococcus aureus -- drug effects
- Survival Analysis
- Treatment Outcome
- Vancomycin Resistance
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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