Population Pharmacokinetics of the TNF-α and IL-17A Dual-Variable Domain Antibody ABT-122 in Healthy Volunteers and Subjects With Psoriatic or Rheumatoid Arthritis: Analysis of Phase 1 and 2 Clinical Trials. [electronic resource]
Producer: 20191126Description: 803-813 p. digitalISSN:- 1552-4604
- Adult
- Antirheumatic Agents -- pharmacokinetics
- Arthritis, Psoriatic -- drug therapy
- Arthritis, Rheumatoid -- drug therapy
- Biological Availability
- Body Weight
- Double-Blind Method
- Female
- Healthy Volunteers
- Humans
- Immunoglobulins -- pharmacology
- Interleukin-17 -- antagonists & inhibitors
- Male
- Metabolic Clearance Rate
- Methotrexate -- therapeutic use
- Middle Aged
- Random Allocation
- Tumor Necrosis Factor-alpha -- antagonists & inhibitors
- Young Adult
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Publication Type: Clinical Trial, Phase I; Clinical Trial, Phase II; Journal Article; Research Support, Non-U.S. Gov't
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