Insulin receptor substrate-4 is overexpressed in colorectal cancer and promotes retinoblastoma-cyclin-dependent kinase activation. [electronic resource]
Producer: 20190614Description: 932-944 p. digitalISSN:- 1435-5922
- Adenocarcinoma -- metabolism
- Adenoma -- metabolism
- Aged
- Aged, 80 and over
- Carcinoma, Hepatocellular -- metabolism
- Cell Line, Tumor
- Cell Membrane -- metabolism
- Cell Nucleus -- metabolism
- Cell Proliferation -- genetics
- Colon -- metabolism
- Colorectal Neoplasms -- metabolism
- Cyclin D1 -- metabolism
- Cytoplasm -- metabolism
- E2F1 Transcription Factor -- metabolism
- Female
- Humans
- Insulin Receptor Substrate Proteins -- genetics
- Insulin-Like Growth Factor I -- pharmacology
- Liver Neoplasms -- metabolism
- Male
- Middle Aged
- Neoplasm Grading
- Neoplasm Staging
- Proliferating Cell Nuclear Antigen -- metabolism
- Protein Transport -- drug effects
- Rectum -- metabolism
- Retinoblastoma Protein -- metabolism
- Signal Transduction
- Up-Regulation
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Publication Type: Journal Article
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