PAR1 agonists stimulate APC-like endothelial cytoprotection and confer resistance to thromboinflammatory injury. [electronic resource]
Producer: 20180725Description: E982-E991 p. digitalISSN:- 1091-6490
- Animals
- Apoptosis
- Endothelial Cells -- metabolism
- Factor Xa -- metabolism
- Gene Knockdown Techniques
- Glycoproteins -- genetics
- Human Umbilical Vein Endothelial Cells
- Humans
- Inflammation -- metabolism
- Lipopolysaccharides
- Male
- Mice
- Mice, Inbred C57BL
- Microcirculation
- Peptide Hydrolases -- metabolism
- Receptor, PAR-1 -- agonists
- Receptors, G-Protein-Coupled -- metabolism
- Signal Transduction
- Thrombosis -- metabolism
- Transcription, Genetic
- Up-Regulation
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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