Characterizing the effects of insertion of a 5.2 kb region of a VACV genome, which contains known immune evasion genes, on MVA immunogenicity. [electronic resource]
Producer: 20180912Description: 55-64 p. digitalISSN:- 1872-7492
- Animals
- CD8-Positive T-Lymphocytes -- drug effects
- Chick Embryo
- Chlorocebus aethiops
- DNA, Viral -- genetics
- Dendritic Cells -- immunology
- Fibroblasts -- immunology
- Genome, Viral
- HEK293 Cells
- Humans
- Immunogenicity, Vaccine
- Interleukin-6 -- genetics
- Interleukin-8 -- genetics
- Lymphocyte Count
- Mice
- Mice, Inbred BALB C
- Mutagenesis, Insertional
- NF-kappa B -- genetics
- Primary Cell Culture
- THP-1 Cells
- Tumor Necrosis Factor-alpha -- genetics
- Vaccinia virus -- genetics
- Vero Cells
- Viral Vaccines -- administration & dosage
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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