Inhibition of COX-2 and 5-LOX regulates the progression of colorectal cancer by promoting PTEN and suppressing PI3K/AKT pathway. [electronic resource]
Producer: 20200504Description: 1-7 p. digitalISSN:- 1090-2104
- Animals
- Arachidonate 5-Lipoxygenase -- metabolism
- Colorectal Neoplasms -- metabolism
- Cyclooxygenase 2 Inhibitors -- pharmacology
- Disease Progression
- Humans
- Lipoxygenase Inhibitors -- pharmacology
- Mice
- PTEN Phosphohydrolase -- drug effects
- Phosphatidylinositol 3-Kinases -- drug effects
- Proto-Oncogene Proteins c-akt -- drug effects
- Signal Transduction -- drug effects
- Tumor Cells, Cultured
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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