AZD9291 Increases Sensitivity to Radiation in PC-9-IR Cells by Delaying DNA Damage Repair after Irradiation and Inducing Apoptosis. [electronic resource]
Producer: 20180619Description: 283-291 p. digitalISSN:- 1938-5404
- Acrylamides -- pharmacology
- Aniline Compounds -- pharmacology
- Animals
- Apoptosis -- drug effects
- Carcinoma, Non-Small-Cell Lung -- pathology
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- DNA Repair -- drug effects
- Dose-Response Relationship, Drug
- Enzyme Activation -- drug effects
- ErbB Receptors -- genetics
- Extracellular Signal-Regulated MAP Kinases -- metabolism
- Female
- Humans
- Lung Neoplasms -- pathology
- Mice
- Mutation
- Proto-Oncogene Proteins c-akt -- metabolism
- Radiation Tolerance -- drug effects
- Time Factors
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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