Comprehensive genomic profiling of head and neck squamous cell carcinoma reveals FGFR1 amplifications and tumour genomic alterations burden as prognostic biomarkers of survival. [electronic resource]
Producer: 20181023Description: 47-55 p. digitalISSN:- 1879-0852
- Adult
- Aged
- Biomarkers, Tumor -- genetics
- Carcinoma, Squamous Cell -- genetics
- Chi-Square Distribution
- Cyclin D1 -- genetics
- Cyclin-Dependent Kinase Inhibitor p16
- Cyclin-Dependent Kinase Inhibitor p18 -- genetics
- DNA Copy Number Variations
- Female
- Gene Amplification
- Gene Expression Profiling -- methods
- Genetic Predisposition to Disease
- Head and Neck Neoplasms -- genetics
- High-Throughput Nucleotide Sequencing
- Humans
- Kaplan-Meier Estimate
- Male
- Middle Aged
- Multivariate Analysis
- Phenotype
- Polymorphism, Single Nucleotide
- Predictive Value of Tests
- Proportional Hazards Models
- Receptor, Fibroblast Growth Factor, Type 1 -- genetics
- Retrospective Studies
- Risk Factors
- Squamous Cell Carcinoma of Head and Neck
- Time Factors
- Transcriptome
- Treatment Outcome
- Tumor Suppressor Protein p53 -- genetics
- Young Adult
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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