Mutations in PI3K110δ cause impaired natural killer cell function partially rescued by rapamycin treatment. [electronic resource]
Producer: 20190819Description: 605-617.e7 p. digitalISSN:- 1097-6825
- Cell Differentiation
- Cells, Cultured
- Class I Phosphatidylinositol 3-Kinases
- Cytomegalovirus -- physiology
- Cytomegalovirus Infections -- genetics
- Cytotoxicity, Immunologic -- drug effects
- Epstein-Barr Virus Infections -- genetics
- Herpesvirus 4, Human -- physiology
- Heterozygote
- Humans
- Immunologic Deficiency Syndromes -- drug therapy
- Immunological Synapses -- metabolism
- Immunophenotyping
- Killer Cells, Natural -- physiology
- Lymphocyte Activation
- Microscopy, Confocal
- Mutation -- genetics
- Phosphatidylinositol 3-Kinases -- genetics
- Sirolimus -- therapeutic use
- Viremia
- Exome Sequencing
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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