MicroRNA-140-5p aggravates doxorubicin-induced cardiotoxicity by promoting myocardial oxidative stress via targeting Nrf2 and Sirt2. [electronic resource]
Producer: 20181011Description: 284-296 p. digitalISSN:- 2213-2317
- Animals
- Cardiotoxicity -- genetics
- Cell Line
- Cell Survival -- drug effects
- Doxorubicin -- adverse effects
- Gene Expression Regulation -- drug effects
- Heart Injuries -- chemically induced
- Humans
- MicroRNAs -- genetics
- Myocardium -- pathology
- Myocytes, Cardiac -- drug effects
- NF-E2-Related Factor 2 -- genetics
- Neoplasms -- complications
- Oxidative Stress -- drug effects
- Rats
- Sirtuin 2 -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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