Unopposed IL-18 signaling leads to severe TLR9-induced macrophage activation syndrome in mice. [electronic resource]
Producer: 20190514Description: 1430-1441 p. digitalISSN:- 1528-0020
- Animals
- Chemokine CXCL9 -- genetics
- Intercellular Signaling Peptides and Proteins -- genetics
- Interferon-gamma -- genetics
- Interleukin-18 -- genetics
- Macrophage Activation Syndrome -- chemically induced
- Mice
- Mice, Knockout
- Nuclear Proteins -- genetics
- Oligodeoxyribonucleotides -- adverse effects
- Signal Transduction -- drug effects
- Toll-Like Receptor 9 -- agonists
- Trans-Activators -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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