Hybrid Pharmacophore Design, Molecular Docking, Synthesis, and Biological Evaluation of Novel Aldimine-Type Schiff Base Derivatives as Tubulin Polymerization Inhibitor. [electronic resource]
Producer: 20180417Description: e1700518 p. digitalISSN:- 1612-1880
- Anti-Bacterial Agents -- chemical synthesis
- Antifungal Agents -- chemical synthesis
- Antineoplastic Agents -- chemical synthesis
- Candida -- drug effects
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Cryptococcus neoformans -- drug effects
- Dose-Response Relationship, Drug
- Drug Design
- Drug Screening Assays, Antitumor
- Gram-Negative Bacteria -- drug effects
- Gram-Positive Bacteria -- drug effects
- Humans
- Microbial Sensitivity Tests
- Molecular Docking Simulation
- Molecular Structure
- Polymerization -- drug effects
- Schiff Bases -- chemical synthesis
- Structure-Activity Relationship
- Tubulin -- metabolism
- Tubulin Modulators -- chemical synthesis
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Publication Type: Journal Article
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