Pirfenidone protects against paraquat-induced lung injury and fibrosis in mice by modulation of inflammation, oxidative stress, and gene expression. [electronic resource]
Producer: 20181003Description: 39-46 p. digitalISSN:- 1873-6351
- Animals
- Anti-Inflammatory Agents, Non-Steroidal -- pharmacology
- Body Weight -- drug effects
- Bronchoalveolar Lavage Fluid
- Fibrosis -- genetics
- Gene Expression -- drug effects
- Gene Expression Profiling
- Herbicides -- toxicity
- Hydroxyproline -- metabolism
- Lung -- drug effects
- Lung Injury -- chemically induced
- Male
- Mice
- Organ Size -- drug effects
- Oxidative Stress -- drug effects
- Paraquat -- toxicity
- Pneumonia -- chemically induced
- Pulmonary Fibrosis -- chemically induced
- Pyridones -- pharmacology
- Reactive Oxygen Species -- metabolism
- Transforming Growth Factor beta1 -- genetics
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Publication Type: Journal Article
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