Hypoxia-induced upregulation of BMX kinase mediates therapeutic resistance in acute myeloid leukemia. [electronic resource]
Producer: 20190507Description: 369-380 p. digitalISSN:- 1558-8238
- Cell Hypoxia
- Child
- Child, Preschool
- Drug Resistance, Neoplasm
- Female
- Gene Expression Regulation, Enzymologic
- Gene Expression Regulation, Leukemic
- Humans
- Infant
- Leukemia, Myeloid, Acute -- genetics
- Male
- Protein-Tyrosine Kinases -- biosynthesis
- Signal Transduction
- Sorafenib -- pharmacology
- Tumor Microenvironment
- Up-Regulation
- fms-Like Tyrosine Kinase 3 -- genetics
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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