Nonclinical Development of ANX005: A Humanized Anti-C1q Antibody for Treatment of Autoimmune and Neurodegenerative Diseases. [electronic resource]
Producer: 20180718Description: 449-462 p. digitalISSN:- 1092-874X
- Animals
- Antibodies, Monoclonal, Humanized -- therapeutic use
- Autoimmune Diseases -- drug therapy
- Complement C1q -- immunology
- Complement Pathway, Classical -- drug effects
- Dose-Response Relationship, Drug
- Drug Evaluation, Preclinical
- Female
- Humans
- Injections, Intravenous
- Macaca fascicularis
- Male
- Neurodegenerative Diseases -- drug therapy
- Rats, Sprague-Dawley
- Species Specificity
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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