Nebulized Heparin Attenuates Pulmonary Coagulopathy and Inflammation through Alveolar Macrophages in a Rat Model of Acute Lung Injury. [electronic resource]
Producer: 20180806Description: 2125-2134 p. digitalISSN:- 2567-689X
- Acute Lung Injury -- blood
- Administration, Inhalation
- Animals
- Anti-Inflammatory Agents -- administration & dosage
- Anticoagulants -- administration & dosage
- Antithrombin III -- metabolism
- Blood Coagulation -- drug effects
- Disease Models, Animal
- Fibrin Fibrinogen Degradation Products -- metabolism
- Heparin -- administration & dosage
- Inflammation Mediators -- metabolism
- Interleukin-6 -- metabolism
- Lipopolysaccharides
- Lung -- drug effects
- Macrophages, Alveolar -- drug effects
- Male
- NF-kappa B -- metabolism
- Nebulizers and Vaporizers
- Neutrophil Infiltration -- drug effects
- Peptide Hydrolases -- metabolism
- Pneumonia -- blood
- Pulmonary Edema -- metabolism
- Rats, Sprague-Dawley
- Signal Transduction -- drug effects
- Thromboplastin -- metabolism
- Transforming Growth Factor beta -- metabolism
- Tumor Necrosis Factor-alpha -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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