Macrovipecetin, a C-type lectin from Macrovipera lebetina venom, inhibits proliferation migration and invasion of SK-MEL-28 human melanoma cells and enhances their sensitivity to cisplatin. [electronic resource]
Producer: 20180522Description: 600-614 p. digitalISSN:- 0304-4165
- Amino Acid Sequence
- Animals
- Antineoplastic Agents -- chemistry
- Antineoplastic Agents, Alkylating -- pharmacology
- Apoptosis -- drug effects
- Apoptosis Regulatory Proteins -- biosynthesis
- Cell Adhesion -- drug effects
- Cell Adhesion Molecules -- biosynthesis
- Cell Line, Tumor
- Cell Movement -- drug effects
- Cisplatin -- pharmacology
- Drug Resistance, Neoplasm -- drug effects
- Drug Screening Assays, Antitumor
- Drug Synergism
- Gene Expression Regulation, Neoplastic -- drug effects
- Humans
- Integrin alphaVbeta3 -- drug effects
- Lectins, C-Type -- chemistry
- Melanoma -- pathology
- Models, Molecular
- Molecular Docking Simulation
- Neoplasm Invasiveness
- Neoplasm Proteins -- biosynthesis
- Protein Conformation
- Protein Interaction Domains and Motifs
- Protein Interaction Mapping
- Sequence Alignment
- Sequence Homology, Amino Acid
- Viper Venoms -- chemistry
- Viperidae -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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