Demonstration of an anti-hyperalgesic effect of a novel pan-Trk inhibitor PF-06273340 in a battery of human evoked pain models. [electronic resource]
Producer: 20190401Description: 301-309 p. digitalISSN:- 1365-2125
- Adolescent
- Adult
- Analgesics -- administration & dosage
- Cross-Over Studies
- Dose-Response Relationship, Drug
- Double-Blind Method
- Healthy Volunteers
- Humans
- Hyperalgesia -- drug therapy
- Male
- Membrane Glycoproteins -- antagonists & inhibitors
- Middle Aged
- Pain Threshold -- drug effects
- Pyrimidines -- administration & dosage
- Pyrroles -- administration & dosage
- Receptor, trkA -- antagonists & inhibitors
- Receptor, trkB -- antagonists & inhibitors
- Receptor, trkC -- antagonists & inhibitors
- Young Adult
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Publication Type: Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
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