Clopidogrel but Not Prasugrel Significantly Inhibits the CYP2C8-Mediated Metabolism of Montelukast in Humans. [electronic resource]
Producer: 20190826Description: 495-504 p. digitalISSN:- 1532-6535
- Acetates -- administration & dosage
- Adult
- Clopidogrel -- administration & dosage
- Computer Simulation
- Cross-Over Studies
- Cyclopropanes
- Cytochrome P-450 CYP2C8 -- genetics
- Cytochrome P-450 CYP2C8 Inhibitors -- administration & dosage
- Drug Interactions
- Female
- Healthy Volunteers
- Humans
- Inactivation, Metabolic
- Leukotriene Antagonists -- administration & dosage
- Male
- Models, Biological
- Oxidation-Reduction
- Pharmacogenetics
- Pharmacogenomic Variants
- Platelet Aggregation Inhibitors -- administration & dosage
- Prasugrel Hydrochloride -- administration & dosage
- Quinolines -- administration & dosage
- Risk Assessment
- Substrate Specificity
- Sulfides
- Young Adult
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Publication Type: Comparative Study; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
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