Variation in the Response of Clozapine Biotransformation Pathways in Human Hepatic Microsomes to CYP1A2- and CYP3A4-selective Inhibitors. [electronic resource]
Producer: 20181001Description: 388-395 p. digitalISSN:- 1742-7843
- Antipsychotic Agents -- metabolism
- Biotransformation
- Clozapine -- analogs & derivatives
- Cytochrome P-450 CYP1A2 -- metabolism
- Cytochrome P-450 CYP1A2 Inhibitors -- pharmacology
- Cytochrome P-450 CYP3A -- metabolism
- Cytochrome P-450 CYP3A Inhibitors -- pharmacology
- Drug Interactions
- Fluvoxamine -- pharmacology
- Humans
- Hydroxylation
- Ketoconazole -- pharmacology
- Liver -- cytology
- Microsomes, Liver -- drug effects
- Oxidation-Reduction
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Publication Type: Journal Article
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