The IKK-related kinase TBK1 activates mTORC1 directly in response to growth factors and innate immune agonists. [electronic resource]
Producer: 20180820Description: 19-38 p. digitalISSN:- 1460-2075
- Animals
- Cell Nucleus -- metabolism
- Cells, Cultured
- Cytosol -- metabolism
- Humans
- Immunity, Innate -- drug effects
- Intercellular Signaling Peptides and Proteins -- pharmacology
- Interferon Regulatory Factor-3 -- genetics
- Macrophages -- drug effects
- Mechanistic Target of Rapamycin Complex 1 -- genetics
- Mice
- Phosphorylation -- drug effects
- Protein Serine-Threonine Kinases -- genetics
- Protein Transport
- Signal Transduction -- drug effects
- TOR Serine-Threonine Kinases -- genetics
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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