Enhancement of therapeutic DNA vaccine potency by melatonin through inhibiting VEGF expression and induction of antitumor immunity mediated by CD8+ T cells. [electronic resource]
Producer: 20180220Description: 587-597 p. digitalISSN:- 1432-8798
- Adjuvants, Immunologic -- administration & dosage
- Animals
- Cancer Vaccines -- administration & dosage
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Epithelial Cells -- drug effects
- Female
- Gene Expression Regulation
- Human papillomavirus 16 -- drug effects
- Interferon-gamma -- genetics
- Interleukin-4 -- genetics
- Lymphocyte Activation -- drug effects
- Melatonin -- administration & dosage
- Mice
- Mice, Inbred C57BL
- Papillomavirus E7 Proteins -- genetics
- Papillomavirus Infections -- immunology
- Papillomavirus Vaccines -- administration & dosage
- Plasmids -- administration & dosage
- Survival Analysis
- T-Lymphocytes, Cytotoxic -- drug effects
- Tumor Burden
- Tumor Necrosis Factor-alpha -- genetics
- Vaccination
- Vaccines, DNA -- administration & dosage
- Vascular Endothelial Growth Factor A -- antagonists & inhibitors
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Publication Type: Journal Article
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