Dampening of the bone formation response following repeat dosing with sclerostin antibody in mice is associated with up-regulation of Wnt antagonists. [electronic resource]
Producer: 20190318Description: 93-103 p. digitalISSN:- 1873-2763
- Adaptor Proteins, Signal Transducing
- Animals
- Antibodies -- pharmacology
- Female
- Glycoproteins -- antagonists & inhibitors
- Intercellular Signaling Peptides and Proteins
- Mice
- Mice, Inbred BALB C
- Osteogenesis -- drug effects
- Peptide Fragments -- blood
- Procollagen -- blood
- Up-Regulation
- Wnt Signaling Pathway -- drug effects
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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