Discovery of a head-to-tail cyclic peptide as the Keap1-Nrf2 protein-protein interaction inhibitor with high cell potency. [electronic resource]
Producer: 20180105Description: 1578-1589 p. digitalISSN:- 1768-3254
- Animals
- Anti-Inflammatory Agents, Non-Steroidal -- chemical synthesis
- Antioxidants -- chemical synthesis
- Dose-Response Relationship, Drug
- Drug Discovery
- Hep G2 Cells
- Humans
- Kelch-Like ECH-Associated Protein 1 -- antagonists & inhibitors
- Lipopolysaccharides -- antagonists & inhibitors
- Mice
- Microscopy, Fluorescence
- Models, Molecular
- Molecular Structure
- NF-E2-Related Factor 2 -- antagonists & inhibitors
- Peptides, Cyclic -- chemical synthesis
- Protein Binding -- drug effects
- RAW 264.7 Cells
- Structure-Activity Relationship
- Tumor Cells, Cultured
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Publication Type: Journal Article
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